Immunoperoxidase Study of the Endolymphatic Sac in Meniere??s Disease
نویسندگان
چکیده
منابع مشابه
Tumors of the endolymphatic sac in von Hippel-Lindau disease.
CONTEXT Endolymphatic sac tumors (ELSTs) are associated with von Hippel-Lindau disease and cause irreversible sensorineural hearing loss (SNHL) and vestibulopathy. The underlying mechanisms of audiovestibular morbidity remain unclear and optimal timing of treatment is not known. OBJECTIVE To define the mechanisms underlying audiovestibular pathophysiology associated with ELSTs. DESIGN, SETT...
متن کاملEndolymphatic sac tumor
Endolymphatic sac tumor is an uncommon, locally aggressive tumor. The tumor is located in the medial and posterior petrosal bone region and may involve the dura. A hypervascular tumor involving the endolymphatic sac with destructive changes, it involves the bone and may show reactive new bone formation. Diagnosis is based on clinical, radiological, and pathological correlation. We present a cas...
متن کاملCharacterization of endolymphatic sac tumors and von Hippel-Lindau disease in the International Endolymphatic Sac Tumor Registry.
BACKGROUND Endolymphatic sac tumors (ELSTs) are, with a prevalence of up to 16%, a component of von Hippel-Lindau (VHL) disease. Data from international registries regarding heritable fraction and characteristics, germline VHL mutation frequency, and prevalence are lacking. METHODS Systematic registration of ELSTs from international centers of otorhinolaryngology and from multidisciplinary VH...
متن کاملThe endolymphatic duct and sac.
The endolymphatic duct (ED) and the endolymphatic sac (ES) are the nonsensory components of the endolymph-filled, closed, membranous labyrinth. The ED leads from the utricular and saccular ducts within the vestibule through the vestibular aqueduct (VA) to the ES, which extends through the distal VA out the external aperture of the aqueduct (Fig 1) to terminate in the epidural space of the poste...
متن کاملEndolymphatic sac tumor.
Endolymphatic sac tumor (ELST) is a papillary epithelial neoplasm arising within the endolymphatic sac/duct that shows a high association with von Hippel-Lindau disease (VHL). There is usually a VHL tumor suppressor gene germline mutation with an autosomal dominant inheritance pattern. Approximately 1 in 35,000 to 40,000 people have VHL, of which approximately 10 to 15% have endolymphatic sac t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Laryngoscope
سال: 1993
ISSN: 0023-852X
DOI: 10.1288/00005537-199309000-00014